{"product_id":"neurocalm-sleep","title":"Metagenics NeuroCalm Sleep","description":"\u003cp\u003e\u003cstrong\u003eFor Sleeplessness And Mild Anxiety\u003c\/strong\u003e\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eIngredients in NeuroCalm Sleep have been used:\u003c\/strong\u003e\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eFor sleeplessness - for a restful sleep, to get to sleep faster and stay asleep longer.\u003c\/li\u003e\n\u003cli\u003eTo relieve mild anxiety, tension and worry.*\u003c\/li\u003e\n\u003cli\u003e* In traditional Chinese and Western herbal medicine.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cbr\u003e\u003cstrong\u003eClinical Benefits\u003c\/strong\u003e\u003cbr\u003e\u003cbr\u003e\u003cspan\u003eNeuroCalm Sleep has sedative qualities which relieve insomnia and mild anxiety. California poppy has traditionally been used for its sedating effects, therefore contributing to a calm and restful sleep. Animal studies have suggested this sedative effect may be due to its ability to bind to GABA receptors and activate them. Lavender oil also acts via GABA receptors and provides additional calming effects by moderating production of stress hormones such as adrenocorticotropic hormone (ACTH), which stimulates cortisol production. Passion flower has an anxiolytic effect by affecting GABA neurotransmitter pathways. Flavonoids from passion flower bind to the stress receptor sites of the GABAA receptor. Zizyphus? calming effects come from its ability to increase the effect of GABA. GABA is a calming neurotransmitter and its activity promotes sleepiness and relaxation.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003eNeuroCalm Sleep reduces effects of excitatory neurotransmitters. Linalool from lavender oil inhibits acetylcholine release and glutamate binding in the cerebral cortex. Its ability to ease tension and promote a restful sleep come from this ability to alter excitatory neurotransmitters such as glutamate and noradrenaline. Zizyphus also reduces the neuroexcitatory effects of glutamate thus reducing wakefulness and alertness.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eDirections\u003c\/strong\u003e\u003cbr\u003e\u003cbr\u003e\u003cspan\u003eAdults: For mild anxiety: Take 1 tablet twice daily with food.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cspan\u003eFor insomnia: Take 2 tablets once daily with your evening meal.\u003c\/span\u003e\u003c\/p\u003e","brand":"Holistic Health Invercargill","offers":[{"title":"Default Title","offer_id":42905823543377,"sku":null,"price":38.5,"currency_code":"NZD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0263\/1047\/5857\/files\/9483229E-F875-4829-ADD7-4EF8A7F99145.jpg?v=1756069726","url":"https:\/\/holistichealth.co.nz\/products\/neurocalm-sleep","provider":"Holistic Health Invercargill","version":"1.0","type":"link"}