{"product_id":"metagenics-ultra-gi-soothe","title":"Metagenics Ultra GI Soothe","description":"\u003cp\u003eA Probiotic To Assist In The Management Of Medically Diagnosed Irritable Bowel Syndrome.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eLactobacillus plantarum?\u003c\/em\u003e299v has been shown to or may:\u003c\/p\u003e\n\u003cul\u003e\n\u003cul\u003e\n\u003cli\u003eAssist in the management of medically diagnosed IBS.\u003csup\u003e1\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eReduce occurrence of IBS symptoms including, gastrointestinal pain, discomfort, bloating and excessive gas.\u003csup\u003e2\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eContains clinically proven, extensively researched exclusive probiotic strain?\u003cem\u003eLactobacillus plantarum?\u003c\/em\u003e299v.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eClinical Benefits\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAround 1 in 5 Australians experience the unpleasant symptoms of IBS at some stage including abdominal pain, mucus in stools, and diarrhoea.\u003csup\u003e1\u003c\/sup\u003e\u003c\/strong\u003eA randomised, double-blind placebo-controlled trial tested the efficacy of\u003cspan\u003e?\u003c\/span\u003e\u003cem\u003eL.plantarum\u003c\/em\u003e299v in 40 people with IBS over four weeks. All patients treated with\u003cspan\u003e?\u003c\/span\u003e\u003cem\u003eL.plantarum\u003c\/em\u003e299v reported significant improvement in stool frequency and complete resolution of their abdominal pain.\u003csup\u003e4\u003c\/sup\u003e\u003cspan\u003e?\u003c\/span\u003eAn overall improvement in all IBS symptoms were noted in 95% of patients in the treatment group, compared to only 15% in the placebo group (Figure 2).\u003csup\u003e5\u003c\/sup\u003e\u003cspan\u003e?\u003c\/span\u003eAnother study involving 204 adults with medically diagnosed IBS found significant symptom improvement within 2 to 4 weeks including abdominal bloating, pain and bowel movements.\u003csup\u003e5\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDefective mucosal intolerance and inflammation:\u003c\/strong\u003e\u003cspan\u003e?\u003c\/span\u003eDisruption of the intestinal barrier can lead to inappropriate inflammatory responses which may occur in IBS. Studies have shown\u003cspan\u003e?\u003c\/span\u003e\u003cem\u003eL.plantarum\u003c\/em\u003e299v to have an effect on barrier function by decrease in permeability\u003csup\u003e7\u003c\/sup\u003e\u003cspan\u003e?\u003c\/span\u003e\u003cem\u003eL.plantarum\u003c\/em\u003e299v has also been shown to exert antipathogenic activity via the production of antimicrobial compounds and inhibiting pathogen adhesion.\u003csup\u003e8\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eA 2016 randomised control trial shows\u003cspan\u003e?\u003c\/span\u003e\u003cem\u003eL.plantarum\u003c\/em\u003e\u003cspan\u003e?\u003c\/span\u003e299v reduces salivary cortisol during stress.\u003csup\u003e9\u003c\/sup\u003e\u003c\/strong\u003e\u003cspan\u003e?\u003c\/span\u003eStress is well recognised as a common trigger for IBS impacting gut secretions, motility, sensitivity and intestinal permeability. A 2016 study on 41 students showed a significant difference in salivary cortisol levels after only 10 days of taking 10 billion CFU.\u003csup\u003e10\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eL.plantarum\u003c\/em\u003e299v is an extensively researched probiotic strain \u003c\/strong\u003ehaving been investigated in at least 140 studies to date, with more than 50 clinical trials.\u003csup\u003e11\u003c\/sup\u003e\u003c\/p\u003e\n\u003ch3\u003eDIRECTIONS\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAdults and children over 5 years:\u003c\/strong\u003eTake 1 capsule daily.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor severe cases:\u003c\/strong\u003eTake 1 capsule twice daily.\u003c\/p\u003e","brand":"Holistic Health Invercargill","offers":[{"title":"Default Title","offer_id":42895933571153,"sku":null,"price":76.9,"currency_code":"NZD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0263\/1047\/5857\/files\/51823934-1D5A-4D3B-963C-B573EE2EAAED.webp?v=1755995425","url":"https:\/\/holistichealth.co.nz\/products\/metagenics-ultra-gi-soothe","provider":"Holistic Health Invercargill","version":"1.0","type":"link"}